Number of AIRE PWM hits (motifs) on human accessible genome:
82,827
Number of summits with AIRE motif per sample (min/median/max):
760 / 1,618 / 4,613
Number of summits with AIRE footprinting per sample (min/median/max):
15 / 47 / 184
Positional profile of TF binding sites
For each transcription factor, positional profile shows where the factor will bind on the regulatory elements. The positions are relative to those summits of regulatory elements. The data are based on motif or footprinting data.
Motif-based (156,877 extended summits (401bp) with AIRE motifs)
Footprinting-based (2,218 extended summits (401bp) with AIRE footprinting)
Density profile of TF binding sites
For each transcription factor, density profile shows how many partners (expressed TFs) may bind to the same regulatory elements. The data are based on motifs or footprinting within 201bp summits.
The number of AIRE partners on the same summit (Motif-based)
Density profile of all expressed TFs in human (Motif-based) Red dot is AIRE.
The number of AIRE partners on the same summit (Footprinting-based)
Density profile of all expressed TFs in human (Footprinting-based) Red dot is AIRE.